Data-driven reweighting of the Charlson and Elixhauser comorbidity indices using German claims data: development for in-hospital mortality only, external validation across clinical and health-economic outcomes
Comorbidity scores such as the Charlson and Elixhauser indices are widely used for risk adjustment in health-economic and clinical outcomes research. Yet the existing weighting schemes, originally designed for mortality prediction, may no longer reflect today’s patient populations or perform equally well across diverse...