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Open access Oct 2026

Longitudinal burden of disease in hypertrophic cardiomyopathy: one-year follow-up of the AFFECT-HCM study

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. However, prospective data on the burden of disease (BoD) remain limited. Baseline results from the AFFECT-HCM cohort reported reduced quality of life (QoL) and increased societal costs among younger (working-aged), symptomatic HCM pat...

R. Mangal, S. Schoonvelde, I. Wiethoff et al. · 0 citations
Open access Oct 2026

Long-term prognostic value of left ventricular outflow tract gradient in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is classified as non-obstructive or obstructive, based on the presence of left ventricular outflow tract (LVOT) obstruction. The threshold for obstructive HCM is ≥ 30 mmHg whereas a gradient ≥ 50 mmHg is generally regarded as the threshold for clinically significant obstruction a...

E. Barba, P. Zwetsloot, A. Hirsch et al. · 0 citations

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