Author

A.-I. Ko

3 papers indexed here

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Open access Nov 2026

The role of climate and immunity in Brazil unprecedented outbreak of dengue in 2024

Brazil experienced a large dengue epidemic during the 2024 season, with almost 5.7 million total cases (compared to under 1.3 million in 2023), raising questions about underlying drivers, including rising temperatures, expansion into susceptible populations, changes in reporting, and novel strains. We compared state-le...

B. Assao Neino, B. Garcia-Carreras, M. Zahid et al. · medRxiv · 0 citations

Open access Oct 2026

Reconstructing Dengue Exposure Dynamics and Assessing the Public Health Impact of Vaccination Scenarios Using Mathematical Models in Brazil

Brazil experienced its worst dengue epidemic in 2024, with an increase in severe outcomes among elderly individuals, highlighting the need for vaccination strategies informed by population immunity. We reconstructed state- and age-specific immune profiles by fitting an age-structured catalytic model to dengue surveilla...

Y. Ko, C. Santos, A.-T. Huang et al. · medRxiv · 0 citations

Open access Sep 2026

Applying a multiplex electrochemiluminescence NS1 assay to detect and differentiate Zika and dengue virus exposures in long-term community cohorts in Brazil and Thailand

Background: Distinguishing Zika virus (ZIKV) from dengue virus (DENV) infection remains a major diagnostic challenge in co-endemic regions due to antigenic cross-reactivity. We evaluated a multiplex electrochemiluminescence Meso Scale Discovery System (MSD) NS1 assay to define ZIKV infection with high specificity acros...

N. Nery, M. Hamins-Puértolas, L. Bahr et al. · medRxiv · 0 citations