Surface-functionalized niosomes using a folic acid-chitosan conjugate for delivery of capecitabine in breast cancer: In vitro and in vivo characterization.
In this study, capecitabine (CAP) niosomes were prepared using the thin-film hydration method with Span 60 and cholesterol as key excipients and the formulation was optimized using a 32 factorial design. The synthesized folic acid-chitosan (FA-CS) conjugate was used to functionalize the niosome surface. An optimized fo...