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Open access Sep 2026

Sex-specific consequences of loss-of-imprinting of the maternally expressed gene Pleckstrin Homology-Like Domain Family A Member 2 (Phlda2) on placental development and fetal growth

Imprinted genes are expressed from one parental allele as a result of epigenetic events initiated in the male and female germlines. We previously identified a role for imprinted genes as master regulators of placental endocrine lineage development in mice. We further reported that loss-of-function of the patern...

A. Chibnall, D. Harrison, E. Lysikova et al. · 0 citations
Open access Sep 2026

Investigating the Contribution of the Imprinted Gene Asb4 to Parental Care

It is proposed that Asb4 supports normal activation of MPOA Gal+ neurons required for parental care and activity of MPOA Gal+ neurons in brain‐specific maternal Asb4 knockout mice and hypothesis knockout animals will demonstrate a deficient behavioural phenotype in one or more parental behavioural characteristics.

Rachel-Ann Jones, Matthew J. Higgs, R. M. John et al. · 0 citations

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