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A. Ito

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Open access Nov 2026

Five-Year Clinical Outcomes Following Nephrectomy for Renal Cell Carcinoma: Evidence From a Nationwide Japanese Surgical Registry.

OBJECTIVES To characterize mid-term oncological outcomes after nephrectomy for renal cell carcinoma (RCC) in Japan using the National Clinical Database (NCD). METHODS We retrospectively analyzed patients with RCC who underwent nephrectomy between April and December 2018 and had at least 5 years of follow-up recorded...

R. Mizuno, Kyoko Yamamoto, Hiroyuki Yamamoto et al. · 0 citations
Open access Oct 2026

Piezo1 Activation by Yoda1 Inhibits Mechanosensitive ATP Release in Human Urothelial Cells and Bladder Overactivity in Rats with Bladder Outlet Obstruction.

Urothelial ATP release during bladder filling modulates afferent nerve activity and detrusor contractility to regulate the micturition reflex, yet the upstream mechanosensory mechanism linking distension to ATP release remains unclear. Here we investigated the role of Piezo1 in regulating mechanosensitive ATP release i...

Shingo Kimura, Kanako Matsuoka, Ádám Lénárt et al. · 0 citations

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