Decreased expression of the PPARG, ADIPOQ, and SLC2A4 genes in subcutaneous adipose tissue in bariatric patients with morbid obesity and type 2 diabetes mellitus
The development of T2DM on the basis of obesity and BMI of more than 35 kg/m 2 is associated with reduced expression levels of the PPARG, ADIPOQ, LEP, LEP and SLC2A4 genes in SAT and VAT, and changes in gene expression in obesity were associated with a decrease in adiponectin and an increase in leptin serum concentra...