Simple Synthesis of Fused 1,3,4-Thiadiazines Through Successive SNAr Processes
A convenient method is described for the synthesis of novel 2-arylazo-1,3,4-thiadiazines fused with pyridine, pyrimidine or pyrazole ring. The synthetic strategy relies on a one-pot tandem cascade that proceeds through three consecutive steps without the isolation of intermediates: (1) nucleophilic aromatic substitutio...