Open access
Jul 2026
High-resolution reconstruction of cell-type-specific transcriptional regulatory processes from bulk sequencing samples.
Deep-learning-based deconvolution of tissue profiles with accurate interpretation of locus-specific signals (DeepDETAILS), a quasisupervised framework performing cross-modality deconvolution using scATAC-seq reference libraries for other bulk datasets, and a potential etiology of the disease are introduced.
Li Yao, Sagar R. Shah, A. Ozer et al.
· Nature Biotechnology · 0 citations