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Author

A. Kabakov

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Open access Sep 2026

Variable Expressivity in Long QT Syndrome Type 2 Rabbits Defines a Low Threshold for Therapeutic IKr Restoration

Long QT syndrome type 2 (LQT2) is caused by pathogenic variants in the hERG potassium channel, resulting in QT prolongation, polymorphic ventricular tachycardia (pVT), and sudden cardiac death. We previously developed a transgenic LQT2 rabbit model that recapitulates the human disease and segregates into two phenotypic...

N. Turan, Allison Welton, Yi-Chun Lu et al. · 0 citations

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