The opportunistic pathogen Pseudomonas aeruginosa ensures its survival by forming mechanically and chemically resistant biofilms, with cationic exopolysaccharide Pel as an abundant constituent of the structural matrix. Despite its biomedical relevance, the mechanisms of Pel synthesis and secretion via the trans-envelop...
Cristian Rosales-Hernandez, Marius Benedens, Julien Reißmann et al.· bioRxiv· 0 citations
Cellular membranes are essentially complex and heterogeneous assemblies. The lipid bilayer forms the basis of the membrane architecture, and the associated proteins and surface-exposed glycans, known as glycocalyx, build up a dynamic, highly crowded environment. This intrinsic crowding modulates diffusion within the li...
M. Schmitter, Laura Hartmann, A. Kedrov· Current Opinion in Structura...· 0 citations
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