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A. Kholikov

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Review Open access Oct 2026

Multi-parameter optimization of recombinant protein secretion in Bacillus subtilis: a review

Bacillus subtilis is widely recognized as one of the most robust and versatile hosts for recombinant protein production. This review provides a comprehensive overview of the protein secretion pathway in B. subtilis, detailing its mechanistic basis and key limiting steps. We discuss the structural features of signal pep...

A. Kholikov, Khushnut Vokhidov, Barno Alimova et al. · 0 citations

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