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Author

A. Kholkumbe

1 paper indexed here

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Review Sep 2026

Heat Shock Protein 90 as a Master Regulator of Multidrug Resistance: Small-molecule Inhibitors, Prodrugs, Hybrid Molecules, Antibody-drug Conjugates, and Nanotechnology-based Delivery Systems.

INTRODUCTION/OBJECTIVE Multidrug Resistance (MDR) remains a major obstacle to effective cancer chemotherapy, driven by multiple interconnected mechanisms, including overexpression of ATP-binding Cassette (ABC) transporters, enhanced DNA repair, apoptosis evasion, and protumorigenic microenvironmental factors. Heat Shoc...

Sundeep Kadasi, A. Kholkumbe, C. Jangme et al. · 0 citations

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