A. Khorgade

Scalable single-cell isoform profiling with sequencing-by-expansion

This work establishes SBX and the AXELIOS 1 as a transformative platform for high-scale single-cell isoform sequencing and demonstrates that this consensus approach successfully captures the vast isoform diversity of single-cell libraries and enables the accurate measure of differential isoform expression across distinct cell types in peripheral blood mononuclear cells.