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Open access Aug 2026

Evaluating phage-antibiotic synergy in differentiated primary airway epithelial cultures against Pseudomonas aeruginosa

Chronic Pseudomonas aeruginosa lung infections are becoming harder to treat due to global escalation of antimicrobial resistance (AMR). Bacteriophage (phage) therapy has emerged as a promising adjunct to conventional antibiotics, especially in chronic lung infections such as those seen in cystic fibrosis (CF). However,...

R. Ng, Alphons Gwatimba, B. Chang et al. · 0 citations
Open access Jul 2026

Long read and short read whole genome sequencing are equivalent for genomic characterisation of bacteriophage: considerations for high throughput analysis

Background Antimicrobial resistance (AMR) is a global health crisis, necessitating alternative antibacterial strategies. Bacteriophages (phages) offer a promising solution, and their use as a therapeutic agent relies on stringent bioinformatic characterisation using whole genome sequencing (WGS) technologies. However,...

Phoebe G. Carr, J. Iszatt, Mitchell G Hedges et al. · 0 citations

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