Author

A. Kitanovic

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Open access Oct 2026

FDX1-independent non-canonical cuproptosis establishes a parallel mitochondria-centric death program

Copper is an essential redox cofactor required for mitochondrial respiration and antioxidant defense, yet its dysregulation creates a therapeutic vulnerability that can be exploited by copper active agents. Elesclomol and neocuproine are two potent copper active compounds, but whether they induce the same form...

Jan Bachmann, Maria-Grazia Molvetti, Anđelija Trajković et al. · Molecular Cancer · 0 citations

Open access Sep 2026

Misfolding of cystathionine beta-synthase impairs mitochondrial homeostasis and cellular bioenergetics.

Homocystinuria (HCU) is an inborn error of metabolism and a conformational disorder chiefly caused by the missense mutations in the cystathionine beta-synthase (CBS) gene. These mutations often cause CBS destabilization, misfolding and dysfunction resulting in CBS deficiency and pathological accumulation of homocystein...

Ela Mijatovic, T. M. Philipp, Karim Zuhra et al. · Free Radical Biology & Medic... · 0 citations

Open access Sep 2026

Comparative characterization of mitochondrial components across size-defined extracellular vesicle populations derived from HaCaT keratinocytes.

The transfer of mitochondrial cargo through extracellular vesicles (EVs) has been reported in several model systems and cell types, yet a detailed characterization of mitochondrial components across different EV populations remains limited. Here, we characterized the mitochondrial cargo of small EVs (sEVs) and large EV...

Finn Brigger, A. Kitanovic, Sébastien Meurant et al. · International journal of pha... · 0 citations