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Author

A. Kleinridders

2 papers indexed here

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Open access Oct 2026

Extracellular GPX3 drives insulin receptor expression in adipose tissue independent of its peroxidase activity

Obesity-associated insulin resistance is driven in part by adipose tissue dysfunction and oxidative stress, yet the role of extracellular mechanisms in modulating insulin signaling remains poorly understood. Here, we show that extracellular Glutathione Peroxidase 3 (GPX3) enhances adipocyte insulin sensitivity and func...

R. Hauffe, M. González, S. Chopra et al. · 0 citations
Open access Sep 2026

Glucose and serum availability fine-tune neuronal metabolic adaptations and direct insulin signaling.

Cell culture systems are indispensable tools for studying cellular metabolism and signaling. However, subtle variations in nutrient composition, serum content, culture duration, and handling can influence cellular physiology. Despite widespread use, conditions commonly regarded as "standard" are rarely systematically e...

L. Reinecke, Hannah Rumpel, J. S. Messner et al. · 0 citations

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