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Author

A. Kowaltowski

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Open access Aug 2026

EP393 - ECE_1290 - Modulation of mitochondrial function and Ca2⁺ dynamics by semaglutide in pancreatic beta cells

GLP-1 receptor agonists such as semaglutide regulate multiple stimulus–secretion coupling components in pancreatic beta cells, integrating metabolic, ionic, and secretory pathways. These agents influence mitochondrial ATP production, membrane excitability, and Ca2⁺ handling, all of which are essential for insulin sec...

É. Vogt, E. Vilas-Boas, Debora Rocha et al. · 0 citations
Open access Aug 2026

Mitochondrial Metabolism and Calcium Handling in Parkinson’s Disease hiPSC-derived Astrocytes

Astrocyte-specific mitochondrial dysfunctions and calcium dysregulation are identified as key features of LRRK2- and PRKN-related pathology, providing new insights into how glial metabolic alterations contribute to neurodegeneration in PD.

Giovanna C. Cavalcante, C. C. Caldeira da Silva, É. Vogt et al. · 0 citations

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