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Open access Oct 2026

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

Abstract Background Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. Objectives To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to identify clinical variables associat...

Daniel Weiss, I. Cebi, Marion Schütt et al. · 0 citations
Open access Jul 2026

Movement dependent neural substates within levodopa-induced dyskinesia in Parkinson's disease.

It is proposed movement execution during dyskinesia should be considered as a distinct behavioral and neural microstate within a dopamine-depending hyperdopaminergic macrostate within a dopamine-depending hyperdopaminergic macrostate to inform future adaptive neuromodulation and enhance its naturalistic robustness duri...

Jeroen G. V. Habets, T. Merk, V. Mathiopoulou et al. · 0 citations

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