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Review Open access Sep 2026

Theranostics for prostate cancer: A Canadian, multidisciplinary expert report

Introduction: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) and PSMA radioligand therapy are changing prostate cancer management, but there is ongoing uncertainty regarding how best to incorporate these approaches into routine practice. This expert report provides C...

A. Lalani, Mina M. Swiha, Sharlini Yogasingam et al. · 0 citations
Open access Aug 2026

Panitumumab-Based EGFR Blockade in SMARCB1-Deficient Renal Medullary Carcinoma: Preclinical Basis and Prospective Clinical Activity

Purpose: SMARCB1-deficient renal medullary carcinoma (RMC) is an ultra-rare, lethal malignancy refractory to therapies approved for other renal cell carcinomas, and its rarity makes randomized trials logistically unfeasible. We investigated whether wild-type epidermal growth factor receptor (EGFR) is a therapeutically...

N. Zacharias, Eric S Rupe, Xinyue Chen et al. · 0 citations

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