Functional redundancy, complementation, and cross-talk between CH25h and IFITM3 in infection and in IFITM3 trafficking and secretion
ABSTRACT Type I interferon induces multiple protein effectors to inhibit viral replication. Among these, the interferon-induced transmembrane protein (IFITM3) and the cholesterol-25-hydroxylase (CH25h) converge on the inhibition of viral entry by altering the behavior of membranes. Here, we dissect the functional and m...