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Review Open access Sep 2026

Exploring the Potential Benefits of Biologic Therapies Beyond Respiratory Allergy

Abstract Severe pediatric asthma is a heterogeneous inflammatory disease that is most commonly driven by type 2 (T2) inflammation. Because respiratory viral infections are the leading triggers of asthma exacerbations in children, this review examines the effects of biologic therapies on infection-related outcomes and a...

Rossella Sica, Francesco Catamerò, Simone Foti Randazzese et al. · 0 citations
Case report Open access Aug 2026

Expanding the spectrum of Sideroblastic Anemia with B-cell Immunodeficiency, Periodic Fever and Developmental Delay (SIFD) syndrome: a case report with new clinical insights and novel genetic variant

This case expands the clinical, immunological, and genetic spectrum of TRNT1-related disease and highlights that immune dysregulation may dominate the clinical course and SIFD should be considered in children presenting with sideroblastic anemia associated with recurrent unexplained inflammation, B-cell immunodeficienc...

Francesco Delle Cave, Ivan Taietti, Annalisa Agostini et al. · 0 citations

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