A. Litke

Learning Biophysical Models of Large-Scale Multineuronal Data to Enable Precise Neurostimulation

Multi-compartment Hodgkin-Huxley (HH) models provide a principled framework for predicting neural dynamics and responses to electrical stimulation. However, fitting HH biophysical parameters typically requires intracellular recordings, which are invasive and low-throughput, limiting the ability to capture the geometry...