The development, interpretation, and validation of AI models as key considerations for their integration and analysis are discussed, and practical suggestions for improving the reliability and biological relevance of AI-driven discoveries are provided.
Yu-Han Sun, Olivia J. Cheng, A. Ma et al.· Genome Biology· 0 citations
The potential of single-cell miRNA profiling to contribute to precision medicine and therapeutic development is outlined, including its possible use in biomarker discovery, monitoring tumor heterogeneity, and informing personalized treatment strategies.
C. Goda, Shaopeng Gu, A. Ma et al.· Methods in molecular biology· 0 citations
Findings indicate MCU-mediated acetyl-CoA metabolism as a critical anti-ferroptosis mechanism, which can be investigated as a potential therapeutic candidate for tumor treatment.
Jianwen Chen, Bao Zhao, Hong Dong et al.· Proceedings of the National...· 1 citation· ⚡1
An integrated single-cell RNA sequencing atlas across mouse models of PKD is constructed, mapping changes in cell type composition, gene expression, and intercellular signaling networks across the whole atlas and within individual models.
S. Miller, Hua Zhong, Weidong Wu et al.· JCI Insight· 0 citations
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