Review
Open access
Sep 2026
Understanding HLA risk in immune-mediated inflammatory diseases requires antigen discovery.
Certain human leukocyte antigen (HLA) alleles occur more often in people with immune-mediated inflammatory diseases (IMIDs) than in unaffected individuals, making HLA one of the strongest inherited contributors to IMID risk. Yet how these alleles promote disease remains unclear. We argue that HLA risk has often been st...
H. ElAbd, A. Mahdy, A. Franke
· Trends in immunology · 0 citations