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Alexander Maier

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Open access Oct 2026

Data-driven reweighting of the Charlson and Elixhauser comorbidity indices using German claims data: development for in-hospital mortality only, external validation across clinical and health-economic outcomes

Comorbidity scores such as the Charlson and Elixhauser indices are widely used for risk adjustment in health-economic and clinical outcomes research. Yet the existing weighting schemes, originally designed for mortality prediction, may no longer reflect today’s patient populations or perform equally well across diverse...

K. Kaier, D. Hazard, A. Heidenreich et al. · 0 citations
Open access Oct 2026

Multi-level thromboinflammatory activation after TAVR: systemic, cellular, and platelet transcriptomic changes

Transcatheter aortic valve replacement (TAVR) induces a thromboinflammatory response characterized by hypercoagulability and dynamic platelet alterations. The integrated mechanisms underlying these changes remain incompletely defined. To comprehensively characterize periprocedural hemostatic and inflammato...

D. Hesselbarth, A. Hoelzle, S. Teegelbekkers et al. · 0 citations
Open access Aug 2026

Safety of Selective and Routine Femoral Access Angiography Post-Transcatheter Aortic Valve Implantation

Background Postprocedural iliofemoral angiography is commonly used to detect access-site complications after transfemoral transcatheter aortic valve implantation (TF-TAVI). However, the clinical value of routine angiographic surveillance remains uncertain. Aims To compare vascular and access-site-related complications...

A. von Ehr, Jonathan Rilinger, Derek Y. Hazard et al. · 0 citations
Open access Jul 2026

Comparative Performance Analysis of an Open Source Motion-Compensated Cardiac Diffusion Sequence Across Different MRI Systems and Gradient Strengths-A Pilot Study.

The presented sequence framework allows for an easy starting point into cardiac diffusion tensor imaging and opens the door to further analysis of hardware impacts on performance.

E. Arbes, Ariel J. Hannum, Johannes Fischer et al. · 0 citations

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