Open access
Sep 2026
Changes in five cerebrospinal fluid and three plasma Alzheimer’s disease biomarkers across increasing brain amyloid-beta and tau pathology burden
A sequential model of biomarker changes across the Alzheimer’s disease neuropathological continuum is supported, with CSF Aβ42/Aβ40 best reflects low/intermediate Aβ burden, while CSF p-tau markers are more closely related to high Aβ and intermediate tau load.
A. Mastrangelo, Simone Baiardi, Edoardo Ruggeri et al.
· Acta Neuropathologica · 0 citations