Author

A. Manne

3 papers indexed here

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Open access Nov 2026

Circulating Tumor DNA Clearance Is Associated with Response and Survival in Metastatic Urothelial Carcinoma Treated with First-Line Enfortumab Vedotin Plus Pembrolizumab

Background/Objectives: Enfortumab vedotin plus pembrolizumab (EV+pembro) is the standard first-line treatment for metastatic urothelial carcinoma (mUC), yet no validated on-treatment biomarker identifies patients deriving a durable benefit. We evaluated whether circulating tumor DNA (ctDNA) clearance is associated with...

Adam Khorasanchi, Sayan Mullick Chowdhury, E. Hong et al. · Cancers · 0 citations

Review Open access Oct 2026

Pancreatic acinar cell carcinoma demonstrates marked clinical heterogeneity and recurrent actionable genomic alterations

Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with a molecular profile distinct from pancreatic ductal adenocarcinoma (PDAC) but is commonly treated using extrapolated paradigms. We retrospectively identified patients with histologically confirmed PACC at a tertiary academic center...

Noor Farhoud, R. Al-Rajabi, J. Baranda et al. · Frontiers in Cell and Develo... · 0 citations

Open access Oct 2026

Outcomes following biliary decompression interventions for jaundiced patients with malignant intrahepatic obstruction from metastatic cancer.

Despite high technical success, only 38% achieved bilirubin ≤2 mg/dL after IBDI and median survival was 7 weeks, highlighting the importance of careful patient selection and earlier goals-of-care discussions.

Tessa Crilley, Adeel Arshad, Mitchell L. Ramsey et al. · JCO Oncology Practice · 0 citations