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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

A. Mantsyzov

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2 papers indexed here

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Aug 2026

Discovery of Highly Potent and Selective, Orally Bioavailable BTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads.

Drugs targeting Bruton's tyrosine kinase (BTK) are recognized as key tools in hematological oncology. The clinical efficacy of BTK inhibitors is limited, however, by the emerging resistance driven by BTK mutations and the severe toxicity attributed to off-target kinase inhibition. PROteolysis TArgeting Chimeras (PROTAC...

A. Mantsyzov, Pei Zhao, Chris Kruse et al. · 0 citations
Open access Aug 2026

Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species

Systematic variation of linker architecture identified compound 28 as a promising exploratory antifungal lead, exhibiting sub-microgram MIC values against several Candida isolates, and retaining measurable activity against an azole-resistant C. albicans strain.

A. Y. Rudenko, Olga A Komarova, A. Y. Simonov et al. · 0 citations

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