INTRODUCTION
Conventional Psoriasis Area and Severity Index (PASI) response rates provide a cross-sectional assessment of treatment effectiveness but do not capture the speed, magnitude, and persistence of clinical improvement. This study evaluated the patient-level cumulative clinical benefit of brodalumab over 52 wee...
L. Potestio, S. Corrao, L. Mastorino et al.· Dermatologic Therapy· 0 citations
Cellular junctions, including desmosomes, hemidesmosomes, adherens, tight, and gap junctions, are essential for epidermal integrity, barrier function, and cell signaling. Variants in genes encoding proteins involved in cellular junctions lead to a spectrum of skin disorders, commonly referred to as junctional genoderma...
Cecilia Del Vecchio, E. Nardacchione, Luisa Zupin et al.· Clinical Dermatology· 0 citations
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