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A. Mason

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Open access Sep 2026

Scorpion venom-derived Opis16a shows potent membrane-destabilising Gram-negative activity and promising in vivo topical efficacy

Antimicrobial peptides (AMPs) are lead candidates for antibacterial drug development, especially against multidrug-resistant Gram-negative bacteria. Previously, we showed that Opis16a, a novel scorpion venom-derived AMP, exhibits broad-spectrum activity against drug-resistant Gram-negative strains with minimal toxi...

Mandelie van der Walt, C. Oosthuizen, A. Mason et al. · 0 citations

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