A. Mazzah

Quinoline Scaffold in Drug Discovery: Synthetic Strategies, Therapeutic Applications, and Emerging Drug Candidates

Quinoline is a bicyclic aromatic heterocycle composed of a fused benzene and pyridine ring, and it has held an important place in medicinal chemistry for nearly two centuries. F. Runge first isolated it from coal tar in 1834, and it was later found to form the structural core of well-known natural products such as quin...

Synthesis, Crystal Structures, DFT Calculations, Molecular Docking Studies Against Cyclin-Dependent Kinase and Molecular Dynamic Simulations of Novel Isatin–Isoxazoline Hybrids