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Author

A. McLysaght

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Open access Aug 2026

A comprehensive and accessible database of jawed-vertebrate ohnologs

Whole-genome duplications (WGDs) profoundly shaped early vertebrate evolution. The set of paralogs retained from these events—“ohnologs”—has had lasting impacts on genome structure and function, including disease gene enrichment. Despite this, we still lack a gold standard ohnolog database. Here, we have harnessed ance...

Łukasz Niezabitowski, Róisín Long, Anthony K. Redmond et al. · 0 citations
Open access Aug 2026

An automated pipeline for reconstructing whole genome duplications

This work develops an automated and user-friendly pipeline for reconstructing ancestral chromosomes before and after WGD, and uses the conservation of gene content to infer chromosomal rearrangement events in this timeframe.

Łukasz Niezabitowski, Anthony K. Redmond, A. McLysaght · 0 citations

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