Open access
Sep 2026
Collapse of embryonic identities and emergence of functional diversity during motor neuron maturation.
Post-mitotic neurons undergo a protracted maturation period as they extend axons to their targets, form synapses, and refine electrophysiological properties. We use temporal single-nucleus multiome sequencing to map molecular underpinnings of maturation in mouse skeletal motor neurons (SMNs). Our data show that SMNs un...
Yi-Jia Chen, H. Chi, Ai Tian et al.
· Cell Reports · 0 citations