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Review Open access Sep 2026

Biomarkers in Clear Cell Renal Cell Carcinoma: From Biological Association to Clinical Decision-Making

Therapeutic options in renal cell carcinoma (RCC) have expanded rapidly, including adjuvant pembrolizumab, HIF-2α-directed therapy, and multiple effective first-line combinations for metastatic clear-cell RCC (ccRCC), yet treatment selection remains largely clinicopathologic. This review evaluates biomarkers at three c...

Hadi Al Etri, Lea Al Zoghby, Mohamad Sadek Zoghbi et al. · 0 citations

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