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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

A. Nogales

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Review Open access Aug 2026

NS-segment-based reporter influenza A viruses: engineering strategy, applications, and limitations

ABSTRACT Reporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host–pathogen interactions, and the identification and characterization of prophylactic and/or therapeutic countermeasures for the treatment of IAV infections. By incorporating a reporter gen...

Ramya S. Barre, H. Nath, A. Nogales et al. · 0 citations
Open access Aug 2026

Genome-Scale Codon Deoptimization Enables Attenuation of Rift Valley Fever Virus

Proof of concept is provided for the use of codon deoptimization (CD) as a rational strategy to generate attenuated RVFV, for the development of next-generation vaccines against this zoonotic threat.

Sandra Moreno, Alejandro Cenalmor, Celia Alonso et al. · 0 citations
Open access Aug 2026

A One-Shot Multivalent Live-Attenuated Candidate Influenza Vaccine against Divergent Zoonotic H5N1 Clades

The development and implementation of this multivalent LAIV as a broadly protective pan-H5N1 LAIV for pandemic preparedness are supported and the feasibility of developing and implementing this multivalent LAIV as a broad protective pan-H5N1 LAIV against divergent H5N1 viruses for human use is demonstrated.

Ahmed M. Elsayed, Ramya S. Barre, Arash Rahmani et al. · 0 citations
Review Open access Jul 2026

Pre-existing and Cross-Reactive Immunity to Avian Influenza H5N1 in Humans: Implications for Pandemic Risk and Vaccine Strategies.

Current evidence on cross-reactive and cross-protective immunity to H5N1 in humans, focusing primarily on humoral immune responses is summarized, and particular attention is given to antibodies targeting conserved regions of hemagglutinin (HA) as well as neuraminidase (NA), which may provide heterosubtypic protection.

Iván Sanz-Muñoz, Carlos J. Ciria-Gil, Marta Hernández et al. · 0 citations
Open access Aug 2026

Enhanced Pathogenicity and Contact Transmissibility of Human-origin Avian Influenza H5N1 Clade 2.3.4.4b Genotype B3.13 Compared to D1.1 in Ferrets

Using the ferret model of influenza infection and transmission, it is demonstrated that the currently circulating B3.3.13 is already well adapted for mammalian infection and transmission whereas D1.1 rapidly acquires mammalian-adaptive mutations after a single infection and/or transmission event, highlighting its evolu...

Ahmed M. Elsayed, Ramya S. Barre, Mahmoud Bayoumi et al. · 0 citations

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