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A. Odainic

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Open access Sep 2026

AI-guided epitope engineering of a SARS-CoV-2 spike antigen for broad sarbecovirus neutralization

These findings show that minimal, structure-guided epitope remodeling can enhance the presentation of conserved epitopes and improve antibody breadth, providing a generalizable framework for designing vaccines resilient to viral evolution and future pandemic threats.

A. Odainic, Ioannis Vardaxis, M. Ferraz et al. · 0 citations

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