Open access
Aug 2026
Defined human Clostridia consortia reverse colitis via dual effects of tryptophan metabolites on microbiota and immunity
SUMMARY Microbial dysbiosis and disrupted mucosal immune homeostasis are integrally involved in the pathogenesis of inflammatory bowel diseases (IBD). Live biotherapeutic products (LBPs) offer a potential therapeutic strategy to restore beneficial microbes and mitigate disease. We investigated the therapeutic efficacy...
A. Oka, G. Bongers, Y. Mishima et al.
· Cell Host and Microbe · 0 citations