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A. Onufriev

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Open access Jul 2026

Reversing aging-like 3D genome disorganization in a Drosophila interphase model

Recent experimental evidence suggests that aging may arise from the progressive deterioration of the epigenetic landscape, while reversing the trend can result in cell and tissue rejuvenation. A mechanistic understanding of how restoration of a key component of this landscape – the 3D structure of the genome – can be a...

A. Onufriev, Jun-Kai Zhang, I. Sharakhov et al. · 0 citations

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