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Oct 2026

52-Week Safety and Disease Control With Ruxolitinib Cream in Children Aged 2 to 11 Years With Atopic Dermatitis: Results From the Phase 3 TRuE-AD3 Study.

BACKGROUND Ruxolitinib (selective Janus kinase [JAK]1/JAK2 inhibitor) cream demonstrated efficacy and safety vs vehicle during 8 weeks of continuous use in a phase 3 study of children with atopic dermatitis (AD). OBJECTIVE To evaluate long-term safety (LTS) and disease control with as-needed ruxolitinib cream use in...

A. Paller, L. S. Stein Gold, E. Simpson et al. · 0 citations
Open access Sep 2026

Efficacy and Safety of Risankizumab in Paediatric Patients With Psoriasis in the OptIMMize-1 Phase III Study.

BACKGROUND Treatment options for paediatric patients with psoriasis are limited, and additional, more advanced therapies are needed. Risankizumab is an interleukin-23 inhibitor approved to treat moderate-to-severe psoriasis in adults. OBJECTIVES To evaluate efficacy and safety of risankizumab through 52 weeks in paed...

N. Magnolo, Wine Lee Lara, A. Reich et al. · 0 citations

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