Sep 2026
The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes.
Unsupervised and supervised machine learning approaches distinguished HCM from dilated cardiomyopathy and accurately predicted genotype status in early-stage HCM from cell type-resolved transcriptional profiles, revealing widespread genotype-driven remodeling.
E. Adami, Yuri Kim, Sean L. Zheng et al.
· Science Translational Medici... · 1 citation