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Author

A. Parikh

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Sep 2026

Abstract B096: Immune and stromal features of durable complete response to radiation and dual immune checkpoint blockade in pancreatic cancer

It is suggested that productive immunotherapy responses in PDAC require not only tumor-reactive T cells, but also a stromal-vascular niche capable of supporting their recruitment, recirculation and persistence.

Sarah Kang, M. Parikh, Leontios Pappas et al. · 0 citations
Review Oct 2026

Pancreatic Reirradiation: A Multi-Institutional Retrospective Analysis of Feasibility, Tolerability, and Clinical Outcomes.

Pancreatic re-RT is feasible and may offer promising local control and time off chemotherapy for selected patients, and improvements in RT delivery with online adaptive therapy may further minimize toxicity.

Helen X. Hou, Hannah J. Roberts, P. Pathak et al. · 0 citations
Sep 2026

Molecular residual disease: Charting a new path for treating resectable solid tumors.

Molecular residual disease (MRD), detected via circulating tumor DNA (ctDNA) after curative-intent surgery, identifies resectable solid tumor patients at high recurrence risk, thereby enabling enriched trials with larger effect sizes and smaller samples. Yet enrichment narrows the eligible population and thus challenge...

S. Kobayashi, T. Hashimoto, H. Bando et al. · 0 citations
Open access Oct 2026

A Phase II Study of Nivolumab and Ipilimumab with Radiation Therapy in Patients with Metastatic, Microsatellite Stable Colorectal Cancer.

PURPOSE Immune checkpoint inhibitors (ICIs) have significantly altered the natural history of microsatellite instability high (MSI-H) colorectal cancer (mCRC). For microsatellite stable (MSS) refractory mCRC, ICIs recently demonstrated efficacy signals in patients without liver metastases. This study evaluated combined...

Leontios Pappas, J. Koenig, B. Yeap et al. · 0 citations
Review Open access Sep 2026

Accelerating equitable cancer genomics and precision oncology in health care and research: a Lancet Oncology Commission.

The Commission developed a value-based resource-stratified implementation framework, a system-readiness assessment tool, a precision oncology workforce competency-based framework, a precision oncology monitoring and evaluation framework, and principles for responsible data sharing and health-system learning.

R. Casolino, J. Mateo, E. D. de Vries et al. · 11 citations

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