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A. Parmeggiani

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Preprint Sep 2026

Enhancer-promoter proximity predicts transcriptional competence but not transcriptional output in the Drosophila brain

How 3D genome architecture contributes to transcriptional specificity across neuronal cell types remains unclear. Here, we used multiplexed chromatin tracing to map chromatin architecture and cell identity at single-cell resolution in the adult Drosophila brain. We found that enhancer-promoter (E-P) proximity was incre...

Olivier Messina, Loucif Remini, Christopher H. Bohrer et al. · 0 citations
Open access Jul 2026

Chromatin tracing at the rut locus in the Drosophila melanogaster adult brain

Five cell-type-resolved chromatin tracing datasets describing chromatin organization at kilobase-scale resolution around the rutabaga locus in the adult Drosophila brain enable future studies of enhancer-promoter organization, chromatin folding, and the relationship between genome architecture, neuronal identity, and g...

M. Bardou, Loucif Remini, Xavier Devos et al. · 0 citations

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