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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

A. Patel

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Open access Oct 2026

Regulatory B cells and the microbiome: implications for checkpoint blockade therapy in cancer

Regulatory B cells (Bregs) restrain effector immunity through interleukin-10 (IL-10), IL-35, and transforming growth factor beta (TGF-β), and their induction depends on signals supplied by the host microbiota. Two mechanistic axes anchor this relationship. Gut commensals drive myeloid IL-1β and IL-6 production, whi...

A. Patel, Gary W. Middleton · 0 citations

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