Author

A. Pekosz

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Open access Sep 2026

Sex and age differences in antibody responses to seasonal influenza vaccination are mediated by estrogenic upregulation of NF-κB and TNF signaling in B cells

ABSTRACT Sex differences in the humoral immune responses to the seasonal quadrivalent influenza vaccine (QIV) in young adults (YA; 18–49 years old) or high-dose QIV in old adults (OA; 75+ years old) were analyzed to determine how age-related changes, including in steroids, impact sex differences in B cells. Among YAs,...

Han-sol Park, Anna Yin, Weiqiang Zhou et al. · mBio · 0 citations

Open access Aug 2026

Influenza A virus H5N1 genotypes B3.13 and D1.1 show temperature-dependent restriction of replication in primary human respiratory epithelial cell cultures derived from the upper and lower respiratory tract

Temperature and not host species may be the primary barrier preventing H5N1 infection in humans, and data suggest that genotype B3.13 and D1.1 may be the primary barrier preventing H5N1 infection in humans.

Anne P. Werner, J. Sachithanandham, E. Akin et al. · bioRxiv · 0 citations

Open access Aug 2026

Genomic surveillance of enterovirus D68 circulating in 2025 reveals the emergence of a novel A2/B3 recombinant lineage

The identification of a novel A2–B3 recombinant lineage provides evidence of ongoing viral evolution through recombination, a mechanism that may alter transmissibility, virulence, or immune responses, and underscores the importance of whole-genome surveillance for accurate viral characterization.

Amary Fall, C. Morris, Omar Elgazayerly et al. · Microbiology spectrum · 0 citations