Author

A. Pérez‐Martínez

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Review Open access Sep 2026

Naive T cell-depleted hematopoietic stem cell transplantation to minimize immunosuppression after solid organ transplantation: case report

Solid organ transplantation (SOT) outcomes remain suboptimal due to graft rejection, drug-related complications and comorbidities. Hematopoietic stem cell transplantation (HSCT) has been explored to induce chimerism and tolerance, reducing reliance on immunosuppression. We report two patients who, post-SOT, received no...

A. Pérez-Martínez, C. Aguirre-Portolés, C. Mestre-Durán et al. · Communications Medicine · 0 citations

Open access Aug 2026

Tisa-cel and axi-cel CAR structure influences the development of resistance to CD19-CAR-T therapy.

CD19-CAR-T cells are a major therapy for relapsed/refractory B-cell malignancies, yet ~50% of patients relapse after infusion. Clinical data suggest that tisa-cel treatment is associated with higher rates of CD19 mutation than axi-cel, though direct comparisons have been lacking. Although both products target the FMC63...

Marta Krawczyk, K. Fidyt, Narcís Fernandez-Fuentes et al. · Leukemia · 0 citations