Gelatin-Based Coating for the Controlled and Localized Delivery of Tetrabranched Antimicrobial Peptide in Cardiac Implantable Devices.
This work proposes the integration of a structurally complex, tetra-branched antimicrobial peptide (SET-M33) within a gelatin methacryloyl (GelMA) hydrogel to create an antimicrobial-releasing coating for CIED surfaces that demonstrated strong in vitro efficacy in preventing bacterial growth and adhesion by six clinica...