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Author

A. Quaegebeur

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Open access Sep 2026

Imaging nanoscopic co-assemblies of α-synuclein and Tau in human samples

α-synuclein (αS), amyloid-β (Aβ), and Tau aggregates are hallmarks of many neurodegenerative diseases, yet the prevalence and nature of their nanoscopic co-assemblies remain poorly understood. Here, we adapt a single-molecule pull-down (SiMPull) assay to profile αS, Aβ, and Tau co-assemblies across post-mortem brain...

Yu P. Zhang, Amber Wallis, Clara Obensa Bertroli et al. · 0 citations

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