Stereochemical Investigation of Paroxetine: Synthesis, Characterization, and Chiral High‐Performance Liquid Chromatography Separation of All Four Stereoisomers
The current work outlines an in‐depth methodology for synthesizing, characterizing, and chiral separation of all four stereoisomers of paroxetine hydrochloride. Paroxetine, having two stereogenic centers, was synthesized via a multi‐step reaction sequence under controlled laboratory conditions, yielding a mixture o...