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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

A. Ramadan

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Open access 2026

A novel approach to sustain delivery of leflunomide from floating gastro-retentive in situ gel for treatment of juvenile idiopathic arthritis: development, in-vitro and in-vivo evaluation

This study aimed to develop and evaluate a floating oral in situ gel with leflunomide (LEF) as a liquid gastro-retentive drug delivery system to increase the residence time of the drug in the stomach and sustain drug delivery. Floating in situ gel system of leflunomide was prepared using sodium alginate as a gelling po...

A. Ramadan, A. Elbakry, Asmaa H. Esmaeil · 0 citations
Oct 2026

Oxcarbazepine-loaded nanoemulsions in thermosensitive nasal gels for epilepsy: in-vitro and in-vivo evaluation in status epilepticus rat model.

To overcome the low aqueous solubility of oxcarbazepine (OXC), a BCS Class II drug, and to enhance brain exposure following intranasal administration, OXC was formulated into a self-nanoemulsifying drug delivery system (SNEDDS) incorporated within a thermosensitive nasal gel. The optimized SNEDDS (SNE.O2), comprising r...

Mina S. Mikhail, Reham M. Essam, Mohamed Salah et al. · 0 citations

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